Royal (Dick) School of Veterinary Studies thesis and dissertation collection
The Royal (Dick) School of Veterinary Studies teaches postgraduate and undergraduate degree programmes, the latter providing the necessary training for a future career as a veterinary surgeon, and undertakes research across a range of veterinary-related fields.Royal (Dick) School of Veterinary Studies is part of The College of Medicine & Veterinary Medicine.
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Recent Submissions
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Effect of the microenvironment on osteoclast driven bone remodelling
(The University of Edinburgh, 2022-05-24)Despite their rigid appearance, bones are dynamic organs going through continuous remodelling cycles. The cells responsible for bone resorption are osteoclasts. Activation of osteoclasts is regulated by hormones, ... -
Characterisation of skeletal development and the use of anabolic agents in murine models of Duchenne muscular dystrophy
(The University of Edinburgh, 2020-08-04)Short stature and osteoporosis are common in Duchenne muscular dystrophy (DMD) and its pathophsyiology may include an abnormality of the growth hormone/insulin-like growth factor 1 (GH/IGF-1) axis, which is further ... -
Equine colic and postoperative ileus: a global study of the veterinary care continuum and proposals for enhanced clinical management strategies
(The University of Edinburgh, 2020-04-04)[No Deposit Agreement] -
Optimising genomic breeding of farmed salmon
(The University of Edinburgh, 2022-03-25)The relatively recent domestication of aquaculture species, such as Atlantic salmon, produces both significant challenges and substantial opportunities for the use of genomic tools in animal breeding which could improve ... -
Genetic analysis of SMOC1 and SMOC2 in eye and limb development
(The University of Edinburgh, 2022-03-18)Secreted modular calcium-binding proteins (SMOCs) are extracellular glycoproteins of the secreted protein, acidic, and rich in cysteine-related modular calcium-binding protein (SPARC) family and include two paralogues ... -
Knowledge and attitudes of veterinarians with regard to pain and welfare in cats: an educational intervention
(The University of Edinburgh, 2021-12-17)Freedom from pain is a key component of animal welfare, and treatment depends on its effective recognition. Since veterinarians play an important role in alleviating animal pain, they must be equipped with the knowledge ... -
Breeding strategies for integrating new and orphan crops in production systems
(The University of Edinburgh, 2021-12-17)In recent decades, plant breeding has shifted toward catering for intensive monocropping based on a few staple crops. This shift has led to a reduction in biodiversity, environmentally-unsustainable agricultural practices, ... -
Apical-out chicken enteroids with leukocyte component as a model to study host-pathogen interactions
(The University of Edinburgh, 2022-03-07)Over the last 20 years global poultry production has tripled with approximately 107 million tonnes of chicken meat and 1.3 trillion eggs now produced every year (FAOSTAT, 2019). Of particular concern for all types of poultry ... -
Optimising beef systems: economic and environmental trade-offs
(The University of Edinburgh, 2022-03-07)Current environmental rhetoric has highlighted the importance of seeking livestock production systems that reconcile competing objectives, especially environmental impacts. Profit margins in cattle systems are small and ... -
Unraveling the effect of sex on human genetic architecture
(The University of Edinburgh, 2022-03-01)Sex is arguably the most important differentiating characteristic in most mammalian species, separating populations into different groups, with varying behaviors, morphologies, and physiologies based on their complement ... -
Chronic wasting disease in Europe: characterisation of genetic susceptibility and strain diversity
(The University of Edinburgh, 2022-03-01)Chronic wasting disease (CWD) is a prion disease that causes a fatal, progressive neurodegenerative disorder in cervid species including deer, elk, reindeer and moose. CWD has become widespread in North America in both ... -
Effects of intrauterine growth restriction (IUGR) on porcine muscle development
(The University of Edinburgh, 2021-12-08)Intrauterine growth restriction (IUGR) is a leading cause of neonatal morbidity and mortality in humans. Preferential allocation of available resources to vital tissues in the IUGR foetus occurs at the expense of ... -
Identification of on-farm recorded data for the prediction of disease in dairy cattle
(The University of Edinburgh, 2021-12-08)Identification of cows at increased disease risk during the transition period is necessary to reduce the negative economic impact of disease and to improve animal welfare. Although timely identification of at-risk cows ... -
Dynamic modelling to explore persistence of disease in endemic settings using foot and mouth disease as an exemplar
(The University of Edinburgh, 2021-12-08)Foot and mouth disease (FMD) costs over $20bn annually in large part due to control costs and production losses. Endemic regions such as sub-Saharan Africa (SSA) are particularly badly affected. Pastoral livestock keepers ... -
Defining immune function and identifying correlates of protection against Chlamydia abortus in sheep
(The University of Edinburgh, 2021-12-08)Chlamydia abortus is an obligate intracellular bacterial pathogen and is one of the most common causes of infectious abortion in sheep world-wide. The organism is responsible for the disease known as ovine enzootic ... -
Developmental counterpart of the Wilms Tumour cancer stem cell
(The University of Edinburgh, 2021-12-08)Wilms tumour (WT; more correctly known as nephroblastoma) is an important childhood renal cancer. The WT cancer stem cell (CSC) has been identified as being a neural cell adhesion molecule-1+ (NCAM1) and aldefluor+ ... -
Dual role of gga-miR-155 in modulating immunogenic and oncogenic responses in avian leukosis virus (ALV) induced B cell lymphomas
(The University of Edinburgh, 2021-12-08)MicroRNAs (miRNAs) are small, single stranded RNA molecules ranging between 19-22nt in length, that are mainly responsible for maintaining cellular homoeostasis by epigenetically regulating the mRNA translation. Each ... -
Short-term measurements and proxies for ruminant methane emissions
(The University of Edinburgh, 2021-12-08)Livestock production is the largest anthropogenic contributor to the global methane (CH4) budget, with enteric emissions estimated to account for 87–97 Teragrams of CH4 per year. Methane is a potent greenhouse gas with a ... -
Dissecting and disrupting the interactions between host cells and the porcine reproductive and respiratory syndrome virus
(The University of Edinburgh, 2021-12-08)Porcine Reproductive and Respiratory Syndrome (PRRS) is the most economically important disease to the swine industry worldwide. PRRS causes reproductive failure and abortion in sows and gilts and respiratory disease, ... -
Controls on ice dynamics of the Greenland ice sheet
(The University of Edinburgh, 2021-11-30)In recent decades, the Greenland Ice Sheet has lost mass at an accelerating rate, such that it is now the largest individual cryospheric contributor to global sea level rise. This mass loss occurs as a combination of an ...
