Preparation and properties of the components of the fibrinolytic system of human plasma
Riding, Isabel M.
Distribution of the antiplasmins is human plasma fractions has been re-investigated, and in addition to the α1 and α2 globulin antiplasmins, a high inhibitory activity was demonstrated in the β-lipoprotein fraction, Cohn Fraction III-O. Ejeperiaents with Fraction 111-0 and norsal seroa established that this antiplasoin was associated with the main β -lipoprotein component. In certain clinieal conditions where the lipoprotein and antiplasmin levels are raised it has been shown that the increase is due to the β -lipoprotein antiplasmin and not to the α antiplasmins. This observation has been correlated with the current theories concerning the aetiology of atherosclerosis.