| dc.contributor.author | Alexander, Frank | en |
| dc.date.accessioned | 2018-01-31T11:22:42Z | |
| dc.date.available | 2018-01-31T11:22:42Z | |
| dc.date.issued | 1944 | en |
| dc.identifier.uri | http://hdl.handle.net/1842/26723 | |
| dc.description.abstract | | en |
| dc.description.abstract | The methods for estimating the histamine
content of blood and tissue were studied and a
simpler procedure adopted. | en |
| dc.description.abstract | The histamine content of normal mice was
determined and it was found that over seventy per
cent of all the histamine in the body was contained
in the skin. | en |
| dc.description.abstract | Large doses of histamine were injected
intravenously in mice and the clearance from the
whole animal studied. The time of half clearance
from the whole body was one and a half hours. | en |
| dc.description.abstract | From the large part of the dose present in
the skin and gut immediately after injection,it
appeared that histamine was rapidly taken up by the
tissues. | en |
| dc.description.abstract | A part of a large dose of histamine,given to
mice,was excreted in the urine, the faeces
contained little more than was normally present.
Excretion only took place whilst a large
concentration was present in the body. | en |
| dc.publisher | The University of Edinburgh | en |
| dc.relation.ispartof | Annexe Thesis Digitisation Project 2017 Block 15 | en |
| dc.relation.isreferencedby | Already catalogued | en |
| dc.title | 1. A study of the distribution of sulphonamides in the body; and 2. study of pharmacologically active substances present in the body by means of biological assays | en |
| dc.type | Thesis or Dissertation | en |
| dc.type.qualificationlevel | Doctoral | en |
| dc.type.qualificationname | PhD Doctor of Philosophy | en |
