| dc.contributor.author | Addison, Patrick | en |
| dc.date.accessioned | 2018-01-31T11:42:28Z | |
| dc.date.available | 2018-01-31T11:42:28Z | |
| dc.date.issued | 2006 | |
| dc.identifier.uri | http://hdl.handle.net/1842/27899 | |
| dc.description.abstract | | en |
| dc.description.abstract | HYPOTHESIS:
That skeletal muscle, throughout the body, can be preconditioned to better withstand
prolonged periods of ischaemia, by first subjecting a remote muscle to brief, non-invasive and sub-lethal, cycles of ischaemia and reperfusion, using a hindlimb
tourniquet. | en |
| dc.description.abstract | AIMS:
The aims of the project were: | en |
| dc.description.abstract | 1) To test the hypothesis, using porcine Latissimus Dorsi, Rectus Abdominis and
Gracilis muscle flaps. | en |
| dc.description.abstract | 2) To define the potency and time course of the protective effect of remote
ischaemic preconditioning in this model. | en |
| dc.description.abstract | 3) To assess the physiological effects of remote ischaemic preconditioning both in
terms of energy metabolism during subsequent prolonged ischaemia, and postischaemic blood flow | en |
| dc.description.abstract | 4) To investigate the mechanism of remote ischaemic preconditioning in this model. | en |
| dc.publisher | The University of Edinburgh | en |
| dc.relation.ispartof | Annexe Thesis Digitisation Project 2017 Block 16 | en |
| dc.relation.isreferencedby | Already catalogued | en |
| dc.title | Remote, non-invasive ischaemic preconditioning of skeletal muscle flaps against ischaemic necrosis : efficacy and mechanism | en |
| dc.type | Thesis or Dissertation | en |
| dc.type.qualificationlevel | | en |
| dc.type.qualificationname | MD Doctor of Medicine | en |
