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On the bacteriological examination of the renal secretion in certain of the zymotic diseases : with subsidiary differential experiments : report of a research conducted as a research student in the Public Health Laboratory of Edinburgh University

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Date
1901
Author
Lewis, Charles James
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Abstract
 
 
At the outset of the investigation it was desired to ascertain whether there is any elimination of pathogenic organisms by the kidney in certain infectious diseases and whether from the Public Health point of view it is essential that the urine should in these diseases be systematically disinfected.
 
The presence of specific microorganisms in the renal secretion in cases of zymotic disease has been described by many observers, more particularly in connection with enteric fever, and the subject possesses not only scientific interest but is of serious practical importance in relation to the spread of disease and the measures to be taken in prevention of infection arising from this source, for, although disinfection of the faeces in enteric fever is recognised as essential and carefully attended to, disinfection of the urine, passed independently of faeces, has not been the routine practice and the question of its continuous necessity throughout the illness may still be regarded as sub judice.
 
To ascertain whether bacteriological examination of the urine in cases of zymotic disease in this neighbourhood would confirm in degree and kind the the positive observations reported elsewhere or would support the negative opinion of other investigators this research was commenced.
 
The Report now submitted deals only with three diseases viz., ENTERIC FEVER, SCARLET FEVER and DIPHTHERIA, and is divided into four main divisions:-
 
I. Historical consideration of the question of renal elimination of organisms.
 
II. Zymotic Bacteriuria.
 
III. An account of the cases examined by myself, with the methods and media employed and the results obtained, and comparison of these with prior research.
 
IV. Subsidiary differential experiments suggested in the course of the research.
 
(a) Sterility of Normal Urine. (b) Urine as a culture medium for Bacillus Typhosus. (c) Organisms identified in the Urine in course of the research, with a note on the different varieties of Bacillus Coli Communis met with. (d) Distinctions and antagonism between Bacillus Coli Communis.and Bacillus Typhosus. (e) Experiments with Medicated Media. (f) Note on Indol Reaction. (g) Tyrosin experiments.
 
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http://hdl.handle.net/1842/28425
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