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Studies on the bacteriology and epidemiology of infections in early infancy

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LudlamGB_1953redux.pdf (35.46Mb)
Date
1953
Author
Ludlam, G.B.
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Abstract
 
 
For about twelve years the writer has been engaged intermittently in field and laboratory studies on certain aspects of infection in infants especially the new -born. His interest in this subject was aroused in 1939 by Professor Charles McNeil who was anxious at the time that the mode of spread of thrush in maternity hospitals should be investigated. The work the writer carried out in this subject is described in Part III of this thesis and some of it has already been published jointly with Dr. (now Professor) J. L. Henderson (Ludlam & Henderson, 1942). It was inevitable that at the same time attention should be attracted by the high incidence of staphylococcal infections in infancy. Research on this was begun and involved much preliminary laboratory work which occupied most of the available time for several years. Later, after the writer had moved to Nottingham the work on staphococci was continued, mainly work on the nasal carriage of Stáah aureus in infancy. Some of this latter work will be published shortly (Ludlam, 1953). While in Nottingham the writer was asked to investigate the aetiology of an outbreak of neonatal pneumonia. The finding of pharyngeal inclusion bodies in the affected infants led to further investigations which resulted in unexpected conclusions that disagreed with previous work on the subject. This research has already been published (Ludlam, 1951). The latter subjects, staphylococcal infection and pharyngeal inclusion bodies, comprise Parts II and IV of the thesis.
 
At the request of a Sub- Committee of the Scientific Advisory Committee of the Department of Health for Scotland, set up to report on neonatal deaths due to infection, the writer prepared a review on the bacteriology and epidemiology of infancy. This was later published (Ludlam, 1947) and has now been modified and brought up to date to form an introduction to the thesis (Part I).
 
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http://hdl.handle.net/1842/28459
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