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dc.contributor.authorBruwer, Henrik Johannesen
dc.date.accessioned2018-03-29T12:21:27Z
dc.date.available2018-03-29T12:21:27Z
dc.date.issued1934en
dc.identifier.urihttp://hdl.handle.net/1842/29460
dc.description.abstracten
dc.description.abstractI. The object of these experiments was primarily to find the influence of the central nervous system on the development of tetanus rigidity and to locate which centres take part in the pathogenesis of the characteristic symptoms.en
dc.description.abstractII. The place of injection had no effect on the distribution of the stiffness. Extensor stiffness resulted whether the injection was made in flexor or extensor muscles.en
dc.description.abstractIII. The position of the limbs before the development of the stiffness was also without influence.en
dc.description.abstractIV. Experiments of hemi -sections of the cord showed that the supra -spinal centres have an influence on the development of rigidity. The extensor stiffness of local tetanus is less marked on the operated side when injections are made in both hind legs.en
dc.description.abstractV. One of the centres which give to the spinal cord the permanent innervation which is necessary for the development of the normal degree of extensor rigidity is the cerebellum. After an extirpation of this centre, extensor rigidity will develop, also on the homo- lateral side, but the degree of rigidity is less than on the non - operated side when bilateral injections are given into the hind legs.en
dc.description.abstractVI. Destruction of the cerebral cortex produced no effect upon the manifestation of tetanus intoxication.en
dc.description.abstractVII. Uni-lateral destruction of the corpus striatum preceding injections of tetanus toxin in both hind legs resulted in flexor rigidity instead of the normal extensor rigidity. This was on both sides, but was more marked on the homolateral one.en
dc.description.abstractVIII. These facts suggest that the corpus striatum has also in normal life an influence on the distribution of tonus.en
dc.description.abstractIX. In treatment of tetanus the method to be preferred is to combine intra-thecal injections of anti-toxin with washing out of the sub-arachnoidal space.en
dc.publisherThe University of Edinburghen
dc.relation.ispartofAnnexe Thesis Digitisation Project 2018 Block 17en
dc.relation.isreferencedbyen
dc.titleThe study of tetanus intoxication and its treatmenten
dc.typeThesis or Dissertationen
dc.type.qualificationlevelDoctoralen
dc.type.qualificationnameChM Master of Surgeryen


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