For the last two years I have been engaged in work
upon the products of the decomposition of blood pigments by means of reducing agents with the view of
elucidating the changes undergone by blood pigment
within the animal organism.
The following Thesis on this subject is divided into
three parts. The first of these consists of a brief
introductory sketch of what is known with regard to
the kataboiism of blood pigment. An historical review of the results obtained by the action of reducing agents upon haematin forms the second part;
while the third part contains an account of the results
which I have obtained from work on the action of reducing agents upon haematin.
Three different methods of investigation may be
adopted for the study of the kataboiism of blood pigment. One may either investigate the changes which
the pigment undergoes in localised extravasations of
blood, or one may study the products of its decomposition which are found, in the excreta under both
normal and pathological conditions, or finally one may
combine with the latter method the investigation of the
effects of experimental interference with the functions
functions of the organs believed to be concerned in
the breaking down of blood pigment with the view of
ascertaining not only the sites of formation of the
various pigment derivatives: but also the nature of
the chemical changes to which they owe their origin.