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Malignant melanoma: a study of 283 cases with comments and suggestions on treatment

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SandemanTF_1963redux.pdf (13.88Mb)
Date
1963
Author
Sandeman, T. F.
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Abstract
 
 
The first and basic result of this study is to show that radiation is by no means useless in malignant melanoma. Even as a palliative it appears to increase survival and certainly is a safer and more sure way of relieving local symptoms than any chemotherapeutic agent yet tried extensively. The fact that the established disease can respond in the great majority of cases has been obscured by the relative minority of spectacular failures.
 
In view of this and the disappointing results of surgery at least in certain situations» e.g. trunk and foot lesions it is perhaps worthwhile trying it in an attempt to improve the results in the elderly, unfit and more advanced case in whom the prognosis evEn with - or perhaps especially with - radical surgery is poor.
 
It would appear that any case with obviously involved nodes is beyond help by surgery alone. DICKSON (1958) has shown the improvement which post-operative radiation can achieve in early cases. It is postulated that in the advanoed case intensive radiation may prolong the patient's life and preserve the functional integrity of his extremities with a better chance of so doing if surgery is not embarked upon.
 
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http://hdl.handle.net/1842/29983
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