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dc.contributor.authorAbreu e Silva, Fernando Antonio.en
dc.date.accessioned2018-05-22T12:37:57Z
dc.date.available2018-05-22T12:37:57Z
dc.date.issued1985
dc.identifier.urihttp://hdl.handle.net/1842/30126
dc.description.abstracten
dc.description.abstractThe primary aim of the research reported in this thesis was to study breathing patterns during sleep in a) apparently normal symptom-free full-term infants, b) infants admitted to hospital during and following recovery from relatively minor illnesses, and c] infants thought to be at increased risk for Sudden Infant Death Syndrome CSIDS) - siblings of previous SIDS victims, and 'near-miss' for SIDS cases, to quantify apnoea (central and obstructive] and observe its effect on heart rate and transcutaneous oxygen tension, PtcO₂. Secondary aims were to study gross body movements (as an indicator of arousal], and to assess whether infants at 'increased risk' for SIDS were chronicallyhypoxaemic during the early months of life. Polysomniographic studies lasting three to five hours during the night recorded eye movements, digastric muscle tone, electrocardiogram^, electroencephalogram, airflow, chest and abdominal movements and PtcO₂ in 86 index cases and 11 healthy controls studied on 176 and 31 occasions respectively.en
dc.description.abstractThe results were as follows:en
dc.description.abstract1. The 11 normal healthy infants did not have episodes of obstructive or prolonged (^-15 seconds] central apnoea during sleep.en
dc.description.abstract2. 33 'symptomatic' infants revealed: a] Bronchiolitis - apnoeic pauses were shorter than 15 seconds. Indices of central apnoea were increased significantly in quiet sleep during the index illness. Prolonged (≥ 6 seconds) obstructive apnoea was uncommon;en
dc.publisherThe University of Edinburghen
dc.relation.ispartofAnnexe Thesis Digitisation Project 2018 Block 19en
dc.relation.isreferencedbyAlready catalogueden
dc.titleClinical studies of breathing during sleep and sudden infant death syndromeen
dc.typeThesis or Dissertationen
dc.type.qualificationlevelDoctoralen
dc.type.qualificationnamePhD Doctor of Philosophyen


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