Chemistry thesis and dissertation collection: Recent submissions
Now showing items 1-20 of 2124
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Studies on the excited electronic states of fullerenes
(The University of Edinburgh, 2020-11-30)This work focused on investigating the excited electronic states of fullerenes. Due to their highly symmetric nature and elemental purity, fullerenes are ideal model systems for studying and understanding the excitation ... -
Investigating the recovery of rare earth elements by ionic liquids and bacteria
(The University of Edinburgh, 2020-11-30)The work presented in this thesis focuses on developing and understanding practices and reagents that can be more efficient at rare earth element (REE) recovery and separation than current industrial reagents and ... -
Enhanced Raman spectroscopy as a tool for the improvement of cervical cancer screening: a comparison of global and targeted approaches
(The University of Edinburgh, 2020-11-30)Half a million women worldwide are diagnosed with cervical cancer annually, with 87% of mortalities occurring in developing economies. HPV vaccination has reduced disease incidence significantly but must be supplemented ... -
Interpretation of the crystal structures of transition metal compounds and complexes
(The University of Edinburgh, 2020-11-30)The Cambridge Structural Database (CSD) contains over half a million structures containing transition metal compounds. The wealth of data available from these structures is enormous and the potential knowledge and insight ... -
Ultrafast photophysics of high-spin metal complexes
(The University of Edinburgh, 2020-11-30)Transition metal complexes (TMCs) show unusual optical, magnetic and chemical properties in comparison to purely organic molecules. These properties make them suitable for several applications. Organic light emitting ... -
Development of novel molecular tools for the characterisation of zebrafish renin
(The University of Edinburgh, 2020-11-30)The renin angiotensin system (RAS) is highly conserved across vertebrates. However, until recently it has not been extensively explored in zebrafish, an important model organism suitable for developmental studies, ... -
New oxidants for arylations with gold
(The University of Edinburgh, 2020-11-30)Gold as an element, has been known for tens of thousands of years, though only recently has the chemistry of gold complexes emerged as an important field for synthetic organic chemistry research. One significant challenge ... -
Development and application of low-cost monitoring approaches for atmospheric ammonia, acid gases and ammonium aerosols
(The University of Edinburgh, 2020-07-30)Ammonia (NH3) is the major alkaline gas in the atmosphere, with around 90 % of the total anthropogenic emissions in Europe coming from agriculture-related sources. Following emission to the atmosphere, the neutralisation ... -
Substituent effects on non-covalent interactions
(The University of Edinburgh, 2020-07-29)Non-covalent interactions play a vital role in biological and chemical systems, underpinning important processes such as ligand–receptor binding and protein structure. Substituent effects on these non-covalent interactions ... -
Investigation of the interactions between fluorescent base analogues and the natural DNA bases
(The University of Edinburgh, 2020-07-25)DNA and RNA are integral to all life on Earth, and yet their physical properties and behaviour in their native environment are still only imperfectly understood. Using fluorescent analogues of natural DNA bases (FBAs) ... -
Ultrafast Imaging of photochemical dynamics via x-ray scattering: connecting theory and experiments
(The University of Edinburgh, 2020-07-25)Although photochemical reactivity has been extensively studied, a clear picture of the underlying dynamics is largely missing predominantly because of the extremely short reaction times involved in these processes. ... -
Elemental and supramolecular diversity of nanoporous phthalocyanine crystals
(The University of Edinburgh, 2020-07-25)Phthalocyanines (Pcs) have a wide variety of applications as colorants, photodynamic therapeutics, photovoltaic materials, catalysts etc. Pcs tend to co-facially aggregate due to the π – π interactions between their ... -
Synthesis, structural and magnetic properties of some transition metal oxides
(The University of Edinburgh, 2020-06-25)The thesis compiles the synthesis and study of several new materials in the perovskite and corundum families. These transition-metal oxide materials have been structurally characterised and their physical properties have ... -
Design and synthesis of novel polymers of intrinsic microporosity for gas separations
(The University of Edinburgh, 2020-06-25)Polymers of Intrinsic Microporosity (PIMs) are a new class of microporous material combining excellent solution processability with great structural diversity. The microporosity of PIMs derives from the inefficient ... -
Improvement of modelling human exposure to NO₂ in cities in China: the case of Guangzhou
(The University of Edinburgh, 2020-06-25)Nitrogen dioxide (NO₂) is an air pollutant identified as a public health concern. Exposure to NO₃ is associated with a number of adverse respiratory health effects, and ultimately with premature mortality. It also contributes ... -
Development of an information theory based computational framework for the analysis of molecular dynamics simulations of proteins under allosteric regulation
(The University of Edinburgh, 2020-06-25)Allosteric signalling was first discovered over 50 years ago, yet the underlying molecular determinants are not yet completely understood. The ability to predict the activity of allosteric small molecules could have a huge ... -
Novel fluorescent probes for monitoring T cell localisation and activity
(The University of Edinburgh, 2020-03-19)Cancer is one of the deadliest diseases known to humanity. In the UK someone is diagnosed with cancer every two minutes. The associated mortality rates vary depending on the type of cancer but despite this being such ... -
Palladium catalysts for cancer imaging
(The University of Edinburgh, 2020-03-19)Lung cancer is one of the most devastating diseases with a 5-year survival rate of 17 %. The reason for this poor prognosis is that the disease is often detected at a late stages because of the reliance on low accuracy/low ... -
Development of a high-throughput drug screening platform for oligodendrocyte myelination (for progressive multiple sclerosis)
(The University of Edinburgh, 2020-03-20)Aim As part of the broad strategy in Edinburgh and beyond to discover new treatments for progressive Multiple Sclerosis (MS), the aims for my PhD project were: (1) to address the lack of an in vitro phenotypic drug ... -
Self-assembling block copolymers in the nucleation of hydroxyapatite
(The University of Edinburgh, 2020-06-25)Dental erosion is a pandemic affecting 3.6 billion people in the world. Over 95 % of enamel is composed of calcium hydroxyapatite (HAP). Enamel is acellular, and as a result of our lifestyle and daily wear and tear this ...
