A total of 107 cases (62 male and 45 female),with histologically
proven malignant disease and all receiving cytotoxic therapy were
A brief review of the history of cancer chemotherapy is given >
together with a detailed account of the principal agents currently
available, methods and routes of administration, means of assessing
response to treatment and the necessary routines of investigation.
The results obtained are presented,mainly in tabular form.
Assessment of response, incidence, severity, significance, mechanisms
and management of toxic effects, the significance of hepatic metas¬
tases and causes of death in relation to oancer chemotherapy, are
discussed in detail.
Finally, the conclusions derived from the study of these cases