Abstract
The application of penicillin to the treatment
of disease ranks with the improved control of malaria
as one of the greatest advances in medicine consolidated during the war years.
Gonorrhoea is but one of many infections amenable to the new antibiotics. Therapy of this disease
is of special interest not only on account of its present wide prevalence but because of all human afflictions it is perhaps that most responsive to penicillin
treatment.
This thesis is limited to a consideration of
the results reported by others and obtained by myself
in male cases with the sodium salt of penicillin. For
the sake of clarity in exposition it is divided into
fuur main parts. In the first a brief account is given
of the properties and mode of action of penicillin
upon which treatment is based; the second describes
the results obtained by others. The third part is an
account of Iv own experiences, clinical and laboratory,
of treatment with single aqueous injections. Finally
a discussion and summary are presented.
(1) Penicillin, its properties, mode of action and
application to the treatment of gonorrhoea
are described.
(2) The results obtained by others are indicated by
reference to the literature.
(3) Personal observations on the results of treatment
by a single injection in aqueous solution are
presented, together with the results of blood
level estimations.
(4) The implications of the foregoing are discussed.
