|dc.description.abstract||This thesis focuses on the development of a malaria vaccine as an avenue
to explore global health partnerships. In the last twenty years, public-private
partnerships have become a prominent organizational form in global health.
Hundreds of large transnational collaborations and countless smaller collaborations
between the public, private and non-profit sectors have been established.
Partnerships have been supported by the large increase of donor funding for
research and control of infectious diseases in impoverished countries and many aim
to develop or provide vaccines, medicines or interventions. Analysts generally
agree that partnerships are saving many lives and revolutionizing drug and vaccine
development for infectious diseases. However, while partnership is a notion that
connotes equity and mutuality, often global health partnerships operate in contexts
that involve vast disparities in power and resources and there is little known about
the impacts of partnerships on the places where they operate. This raises the
questions: How do global health partnerships operate in practice? What are their
impacts in the places where they operate?
Addressing these questions, this thesis examines a partnership established
to develop the most advanced malaria vaccine, named RTS,S. Based on 17
months of ethnographic research in Tanzania and interviews with representatives of
partnering organizations in Belgium and the United States, I trace the development
of the RTS,S vaccine from laboratories to its clinical trials across Africa. I explore
the social relationships formed between private companies, philanthropic institutions
and non-profit organizations in the North, and research institutions and communities
in north-eastern Tanzania, where a malaria vaccine clinical trial was conducted.
Analyzing the impacts of the malaria vaccine partnership, I focus on community
development, construction of infrastructure, the building of human capacity,
provision of health care and extraction of data. The focus on partnerships is
intended to improve understanding about this ever-increasing social, political and
economic formation in global health, and contributes to discussions and debates
about how partnerships operate and their role in international development, global
health governance and transnational medical research.||en