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dc.contributor.authorRaeburn, Johnen
dc.date.accessioned2019-02-15T14:17:30Z
dc.date.available2019-02-15T14:17:30Z
dc.date.issued1951
dc.identifier.urihttp://hdl.handle.net/1842/33610
dc.description.abstracten
dc.description.abstractIt may be concluded that 3-keto-2:3-dihydrobenz-1:4-thiazine and its derivatives, with the exception of the unsubstituted compound itself and the 6-nitroso-derivative both of which have a slight stimulant effect, have no effect on the 'intermediate' preparations of Ascaris.en
dc.description.abstractAll but six, namely the 6-arsonic and stibonic acids, the 6-mercuric chloride compound, the 6-amino compound coupled with phloroglucinol and salicylic acid, and 6:6'-bis-(3-keto-2:3-dihydrobenz-1:4-thiazine), have a paralysant effect on liver fluke, the 6-amino and 6-thiol compounds being almost lethal at a concentration of 1 in 1000.en
dc.description.abstractWe may, therefore, conclude that certain atoms or groups increase the activity, whilst others decrease the activity of 3-keto-2:3-dihydrobenz-1:4-thiazinne towards liver fluke. The inactivity towards Ascaris may be partly due to the inability of the compounds to penetrate the Ascaris cuticle, a difficulty which it might be possible to overcome by using a suitable wetting agent.en
dc.publisherThe University of Edinburghen
dc.relation.ispartofAnnexe Thesis Digitisation Project 2019 Block 22en
dc.relation.isreferencedbyen
dc.titleThe influence of groups in the molecule of 3 - keto - 2:3 - dihydrobenz - 1:4 - thiazine on its “antheimintic” propertiesen
dc.typeThesis or Dissertationen
dc.type.qualificationlevelDoctoralen
dc.type.qualificationnamePhD Doctor of Philosophyen


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