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dc.contributor.authorMasson, George Airden
dc.date.accessioned2019-02-15T14:35:19Z
dc.date.available2019-02-15T14:35:19Z
dc.date.issued1926en
dc.identifier.urihttp://hdl.handle.net/1842/35162
dc.description.abstracten
dc.description.abstractThe doses are stated in terms of milligrams of bismuth metal per kilo, injected, of course, in the form of bismuth sodium tartrate; the small doses mentioned were in all cases the first injections in the experiments, and the injections have been made over approximately the same length of time. From, the manner in which the experiments were conducted, nearly all the large doses followed on a previous smaller 'one and thus the relation with them between dose and effect is not strictly accurate.en
dc.description.abstractMinimum, and maximum doses which produced changes in the heart, and blood pressure:en
dc.description.abstract0.45 to 0.54 mgs. bismuth metal per kilo, gave a slight fall in blood pressure and lessening of the amplitude, and slowing, of the heart.en
dc.description.abstract1.54 to 1.78 mgs. bismuth metal per kilo, gave a marked fall in blood pressure and marked lessening of amplitude, irregularity and slowing of the heart, and if repeated in the course of the experiment, gave more pronounced slowing, lessening of amplitude and death of the heart.en
dc.description.abstract2.67 mgs. bismuth metal per kilo, gave marked irregularity, lessening of amplitude and temporary stopping of the heart.en
dc.description.abstractReference to the determination of the lethal dose of bismuth in cats shows that the minimum fatal dose is ten times the minimum dose which gives slight changes in the heart and blood pressure.en
dc.publisherThe University of Edinburghen
dc.relation.ispartofAnnexe Thesis Digitisation Project 2019 Block 22en
dc.relation.isreferencedbyen
dc.titleExperimental investigations into the toxicity of bismuth with special reference to its action on the circulatory systemen
dc.typeThesis or Dissertationen
dc.type.qualificationlevelDoctoralen
dc.type.qualificationnameMD Doctor of Medicineen


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