Engineering thesis and dissertation collection
Recent Submissions
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Electrically directed gene expression (EDGE): using switchable DNA triplexes and electrolysis to modulate transcription in a cell-free medium
(The University of Edinburgh, 2023-01-25)External control of gene expression is a powerful tool for molecular biology that benefits both research and commercial applications. Being able to control genetic systems using electrical signals would enable more ... -
Tidal stream power resource assessment of the Churchill Barriers in the Orkney Islands, Scotland
(The University of Edinburgh, 2023-01-25)In order to tackle climate change challenges, various renewable energy sources are required to provide sufficient energy to phase out fossil fuel and decarbonise electricity generation. This research project aimed to present ... -
Low carbon multi-vector energy systems: a case study of the University of Edinburgh's 2040 'Net Zero' target
(The University of Edinburgh, 2023-01-20)The ultimate goal of this research was to develop a methodology to support decision-making by large (public sector) organisations regarding future energy technology choices to reduce carbon emissions. This culminated ... -
Impact of peer-to-peer trading and flexibility on local energy systems
(The University of Edinburgh, 2023-01-20)To meet the 2050 net zero emission targets, energy systems around the globe are being revisited to achieve multi-vector decarbonisation in terms of electricity, transport, heating and cooling. As energy systems become more ... -
Surface-enhanced Raman scattering (SERS) pH sensors for cancer and cystic fibrosis in vitro disease models Surface-enhanced Raman scattering (SERS) pH sensors for cancer and cystic fibrosis in vitro disease models
(The University of Edinburgh, 2023-01-20)The development of pH sensing tools for in vitro cell cultures is imperative to maximize the pathophysiological knowledge the scientific community can extract from disease models. Surface-enhanced Raman scattering (SERS) ... -
Data-driven short-term load forecast method and demand-side management for distribution network
(The University of Edinburgh, 2023-01-17)With the development of the power grid, the smart grid makes the system more intelligent, efficient, sustainable and reliable with integrated Information and Communication Systems. Moreover, the data from the advanced ... -
Morphology optimization of ordered chromatography stationary phases: a workflow designed by machine learning and computational fluid dynamics
(The University of Edinburgh, 2023-01-12)Chromatography is a significant separation and analysis method widely used in analytical chemistry and biochemistry. A chromatographic system contains a mobile phase and a stationary phase, where the commonly utilized ... -
Development of an adsorption differential volumetric apparatus for accurate measurement of mass transfer in nanoporous materials
(The University of Edinburgh, 2023-01-10)The volumetric technique is a widely used macroscopic method to measure gas adsorption kinetics in nanoporous materials, however, there are some common pitfalls in measurement practices which can lead to significant deviation ... -
Investigations on advanced joining methods for composite materials and fibre reinforcements
(The University of Edinburgh, 2022-12-22)Fibre Reinforced Plastics (FRPs) are heavily utilised in high performance engineering applications due to their exceptional physical characteristics, including excellent specific strength, stiffness, fatigue loading ... -
Electrospun piezoelectric polymer 3D structures for wearable energy harvesters
(The University of Edinburgh, 2022-12-22)Wearable devices have emerged as one of the most rapidly growing branches of the consumer electronics industry in recent years. Having a wide breadth of applications, ranging from leisure and fitness tracking to therapeutics ... -
Understanding the heat transfer, pyrolysis and ignition of wildland fuels
(The University of Edinburgh, 2022-12-20)This work provides an understanding of the heat transfer, pyrolysis and ignition of wildland fuels. To do so the wildland fuel morphology, thermal degradation and flammability were assessed through experimentation and ... -
In-situ diagnostics of the packed bed in post-combustion CO₂ capture using electrical capacitance tomography
(The University of Edinburgh, 2022-12-20)Climate change is commonly acknowledged as a result of increased greenhouse gas levels in the atmosphere. The excess use of fossil fuels and consequential emission of greenhouse gases is causing global warming. Global ... -
Dynamic response analysis of floating offshore wind turbines with failed moorings
(The University of Edinburgh, 2022-12-19)Offshore wind energy is turning to a mainstream energy source due to the advantages of low emission, high efficiency and abundant reserves. The deployment of offshore wind turbines has accelerated during the past decade ... -
Data-driven modelling, forecasting and uncertainty analysis of disaggregated demands and wind farm power outputs
(The University of Edinburgh, 2022-12-16)Correct analysis of modern power supply systems requires to evaluate much wider ranges of uncertainties introduced by the implementation of new technologies on both supply and demand sides. On the supply side, these ... -
Mechanical properties of asymmetric bouligand structured carbon fibre reinforced plastics
(The University of Edinburgh, 2022-12-16)This thesis adopted two novel bioinspired microstructural approaches for the purpose of investigating the effect of inter-ply pitch angles on the tensile and viscoelastic behaviours of composite structures. Two bioinspired ... -
Design of microbial cell factories using integrated synthetic biology and systems biology for the production of Taxol®, an anticancer drug
(The University of Edinburgh, 2022-12-15)The cytochrome P450 enzymes play indispensable roles in the biosynthesis of natural products. The industrially compatible development of these biocatalysts relies on understanding their functionalities in the context of ... -
Data-driven microwave imaging and processing techniques for monitoring neurodegenerative diseases
(The University of Edinburgh, 2022-12-14)Neurodegenerative diseases, such as Alzheimer’s disease (AD), affect cognitive functions and behaviour due to the progressive loss of neurons in the human brain. Unfortunately, although medicines can help relieve some ... -
Transport, selectivity and antifouling in nanoscale membranes
(The University of Edinburgh, 2022-11-24)Desalination of seawater has been pursued since ancient times, first being recorded around 300 BC, largely to provide drinking water in ocean-going vessels. The primitive means used then depended on distilling seawater, ... -
Designing yeast cell factories to produce early-step Taxol® precursors: from CRISPR toolkit development to computer-aided design and optimisation of a CRISPR-based molecular diagnosis method
(The University of Edinburgh, 2022-12-14)CRISPR methods for yeast generally rely on pre-assembled DNAs and extra cloning steps to deliver gRNA, Cas protein, and donor DNA. These laborious steps might hinder its usefulness. In this thesis, I propose a convenient, ... -
Design and development of drug co-delivery platform for enhanced anti-tumour efficacy
(The University of Edinburgh, 2022-12-13)Combination therapy, often referring to the administration of two or more therapeutic agents with different functional sites in cancer cells, has been used to address the efficacy of chemotherapy in clinical application. ...
