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dc.contributor.authorMilne, Ian Rossen
dc.date.accessioned2019-02-15T14:37:11Z
dc.date.available2019-02-15T14:37:11Z
dc.date.issued1946en
dc.identifier.urihttp://hdl.handle.net/1842/35346
dc.description.abstracten
dc.description.abstractIn series A, 2 children were examined wiith urine and stool examination, Eosinophil. Counts, and Cercarial Skin Test Antigen.en
dc.description.abstract15 cases with ova demonstrable, gave raised Eosinophil Counts and + positive Skin Tests. In series B, 30 adult male Railway employees were similarly investigated. 8 cases has ova demonstrable in either urine or stool. All gave a + positive skin test, but Eosinophil :Dounts did not snow a consistent rise. Cases Nos. 11, 12 and 19 alone had percentage counts above normal limits. In -series C, 33 adult male private patients were similarly investigated. Only one case was found to nave demonstrable ova, the case gave a positive skin test and the Eosinophil count was normal.en
dc.description.abstractIn series D 18 adult private patients were similarly investigated. None showed demonstrable ova in urine or stool. One case (No. 18) with a previous history of S. mansoni infestation was found to have a very high Eosinophilia and a doubtful skin test reaction. This case was further investigated by crystoscopy and sigmoidoscopy with negative findings and a diagnosis of Tropical Eosinophilia was finally mace.en
dc.description.abstractIn the cases where ova were present in urine and stool: - In series A, three children gave positive skin test, Eosinophilia and history of risk of infestation. Two children gave doubtful skin test, normal Eosinophilia Counts and risk of infestation, and nine children gave negative skin test, normal Eosinophil Counts and possible risk.en
dc.description.abstractIn series B, seven cases of Railwaymen gave positive skin test, and normal Eosinophil Counts, except in 2 cases where Eosinophilia was present. Three cases of Railwaymen gave doubtful skin test - one only had an Eosinophilia, and eleven cases of Railwaymen gave negative skin test - two only had an Eosinophilia. All these cases ran an occupational risk of infestation. In series C, two cases gave a positive skin test, normal Eosinophil Counts and risk of infestation. Five cases gave a doubtful skin test, normal Eosinophil Counts and risk of Infestation, and twenty-five cases gave a negative skin test, Eosinophilia was present in 4 cases only, and risk of infestation was doubtful. In series D, two cases gave a positive skin test, both had Eosinophilia and risk of infestation was unlikely. One case gave a doubtful skin test, a very high Eosinophilia, and a history of old S. mansoni infestation of 4 years duration, and fourteen cases gave a negative skin test, five of whom has an Eosinophilia. The risk of infestation in all these cases was very improbable.en
dc.description.abstractIn a review of the cases in the series A, B, C, and D, it is apparent that: - 1. The demonstration of ova in urine and stool is positive evidence of the disease; that in such cases the Cercarial Skin Test Antigen gives a positive reaction in every case, and that the Eosinophil Percentage Count is not a completely reliable test in such cases. • 2. Absence of ova in urine and stool in a case does not necessarily imply freedom from the disease as such cases do not. always give a negative Cercarial Skin Test Antigen Reaction, nor is the Eosinophil Percentage Count always within normal limits. Should, however, the Cercarial Skin Test Reaction be a negative one, and the Eosinophil Count is normal, then it is practically certain the case is not one suffering from Schistosomiasis. • 3. Absence of ova in urine and stool in a case giving a positive Cercarial Skin Test Antigen may or may not mean the presence of Schistosomiasis, even with an Eosinophilia. • 4. The absence of ova in urine and stool in a case giving a doubtful Cercarial Skin Test Antigen Reaction may or may not mean the presence of Schistosomiasis, and that, with or without an Eosinophilia. In cases complying with categories 3 and 4, further intensive investigations are called for by cystoscopic and sigmoidoscopic examinations as well as further examinations of urine and stool specimens, etc. From this examination and analysis the author concludes that; - The children in S. Rhodesia are very liable to infestation by Schistosomiasis. The employees on the Rhodesian Railways in tn.e course of their occupation run a very grave risk of becoming infested, and The men and women engaged in their ordinary pursuits of life in cities of S. Rhodesia are the least likely subjects to fall victim to the disease.en
dc.publisherThe University of Edinburghen
dc.relation.ispartofAnnexe Thesis Digitisation Project 2019 Block 22en
dc.relation.isreferencedbyen
dc.titleA clinical study of schistosomiasis in the European resident in Southern Rhodesia: with particular reference to new methods of diagnosis and treatmenten
dc.typeThesis or Dissertationen
dc.type.qualificationlevelDoctoralen
dc.type.qualificationnameMD Doctor of Medicineen


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