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dc.contributor.authorVisscher, P Men
dc.contributor.authorSmith, Den
dc.contributor.authorHall, SJGen
dc.contributor.authorWilliams, JLen
dc.coverage.spatial1en
dc.date.accessioned2005-02-09T17:00:37Z
dc.date.available2005-02-09T17:00:37Z
dc.date.issued2001-01-18
dc.identifier.citationVisscher PM, Smith D, Hall SJG, Williams JA, NATURE, 409 (6818): 303-303 JAN 18 2001
dc.identifier.urihttp://hdl.handle.net/1842/690
dc.description.abstractInbreeding, which can lead to the loss of genetic variation or the accumulation of deleterious alleles, has been shown to reduce fitness in wild (1), zoo, laboratory (2) and farmed (3) animals. But it has been proposed that when combined with selection, inbreeding may purge deleterious alleles (4). Here we provide support for this hypothesis in a study of the Chillingham cattle, which shows that this viable herd is almost genetically uniform. The homozygosity of this herd far exceeds that of other cattle (5) and that found in wild populations of other mammalian species (6,7).en
dc.format.extent183923 bytesen
dc.format.mimetypeapplication/pdfen
dc.language.isoen
dc.publisherNature Publishing Groupen
dc.subjectherden
dc.subjectgeneticallyen
dc.subjectuniformen
dc.subjectcattleen
dc.subjectDeleteriousen
dc.subjectallelesen
dc.subjectferal strainen
dc.subjectinbreden
dc.subjectcowsen
dc.titleA viable herd of genetically uniform cattle - Deleterious alleles seem to have been purged in a feral strain of inbred cowsen
dc.typeArticleen


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