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Loss of Dicer fowls up centromeres

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loss_of_dicer.pdf (151.9Kb)
Date
08/2004
Author
White, Sharon A
Allshire, Robin C
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Abstract
Centromeres, specialized regions on chromosomes, are essential for accurate chromosome segregation during cell division. In fission yeast, the RNA interference machinery has a pivotal function in the assembly of centromeric heterochromatin, which mediates sister centromere cohesion. Studies in vertebrate cells now suggest that many aspects of this process are conserved.
URI
doi:10.1038/ncb0804-696

http://www.nature.com/nature

http://hdl.handle.net/1842/716
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  • Biological Sciences publications

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