Chemistry, School of: Recent submissions
Now showing items 1-20 of 2263
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Polymers of Intrinsic Microporosity for aqueous organic Redox flow batteries
(The University of Edinburgh, 2021-11-27)Redox flow batteries (RFBs) based on aqueous organic electrolytes are promising technologies for large-scale, safe and cost-effective electrical energy storage. The membrane separator is the key component in a RFB system ... -
Phase stability in molecular materials at extreme conditions of temperature and pressure
(The University of Edinburgh, 2021-11-27)Understanding phase stability and polymorphism in molecular materials is of importance in applications such as energy storage, optoelectronics and pharmaceuticals. The pharmaceutical industry invests billions of pounds ... -
Effect of workplace mobility on air pollution exposure and its inequality in the UK
(The University of Edinburgh, 2021-11-27)A large number of epidemiological studies have identified air pollution as a major risk to human health. Short-term and long-term exposures to air pollutants such as PM2.5, NO2 and O3 cause cardiovascular and respiratory ... -
Hydrolytic stability and protodeboronation of boronic esters
(The University of Edinburgh, 2021-11-27)Boronic acids and esters are indispensable building blocks in modern synthetic chemistry. Furthermore, their usage is widespread, spanning a broad range of applications, and yet it is often hampered by the inescapable ... -
Investigating the synthesis of ettringite and monosulfate analogue phases and their use as waste remediation materials
(The University of Edinburgh, 2021-11-27)Pollution from industrial sources into freshwater supplies is a growing global problem with 80 % of all wastewater produced being released into the environment with no treatment. This poses a risk to both human and ... -
Harnessing coordination cage electrostatics to unlock bio-inspired catalysis
(The University of Edinburgh, 2021-11-27)Synthetic supramolecular host molecules are able to mimic enzymes by using their cavities as an artificial active site. Previous research has shown that synthetic hosts are able to accelerate chemical transformations using ... -
Bioenergy plantations: assessment of biogenic volatile organic compounds from short-rotation forests and their potential impact on UK air quality
(The University of Edinburgh, 2021-11-27)The UK government has committed to a net-zero greenhouse gas (GHG) emission target by 2050. Bioenergy technologies are a dominant feature in the pathways to achieving this target. It is suggested that 0.7 million hectares ... -
Exploration of structure – property relationships in nitropyrazole-based energetic materials using co-crystallisation and high pressure
(The University of Edinburgh, 2021-11-27)Energetic materials are chemical compositions that can rapidly release large amounts of energy when suitably triggered by impact, shock, spark or friction. Key properties of energetic materials include detonation velocity, ... -
Mono- and multi-metallic main group salen complexes: applications in lactide ring-opening polymerisation
(The University of Edinburgh, 2021-11-27)Ligand-metal complexes have demonstrated high potential for catalytic control over the ring-opening polymerisation (ROP) of rac-lactide. Catalyst performance and control over the resultant polymer structure can be ... -
Rhenium polyhydride complexes of boron-hydride ligands and their application in catalysis
(The University of Edinburgh, 2021-11-27)The synthesis of transition metal complexes containing metal-boron bonds is of particular interest due to the relevance of these complexes as intermediates in catalytic C–X (X = H or halogen) borylation to prepare ... -
Using host-guest chemistry to manipulate magnetic interactions in metallosupramolecular M4L6 tetrahedral cages
(The University of Edinburgh, 2021-11-27)The process of self-assembly, which exploits reversible interactions, has allowed the construction of metallosupramolecular cages (MCs) from simple building blocks. MCs possess internal cavities that can be used to encapsulate ... -
Redox-active di(heteroaryl)methenes as ligands for electron transfer reactions
(The University of Edinburgh, 2019-07-01)As a consequence of the discovery of ligand non-innocence, the last few decades have seen the chemistry of coordination complexes being re-evaluated. Compared to their counterparts, non-innocent ligands are actively involved ... -
From electrolytes to hole transport materials in dye-sensitised and perovskite solar cells
(The University of Edinburgh, 2021-07-31)Dye-sensitised solar cells (DSSCs) and perovskite solar cells (PSCs) have brought new impetus to the photovoltaic research field due to their artistry such as colour and flexibility, and stable performance under ... -
Optical fibre chemical sensors and biosensors based on fluorescent polymers
(The University of Edinburgh, 2021-07-31)Optical fibre-based pH sensors have been well explored and studied for physiological use since the development of the first optical fibre pH probe in 1980. However, the need for robust attachment of pH reporters onto ... -
Cell surface imaging and bioorthogonal chemistry
(The University of Edinburgh, 2021-07-31)The labelling of the plasma membrane with targeted fluorescent probes offers a convenient and non-invasive means to image the cell membrane and follow morphological changes and dynamics in real-time. However, despite ... -
Aromatic interactions in solution
(The University of Edinburgh, 2021-07-31)Non-covalent interactions underpin a vast array of molecular recognition phenomena including drug binding and asymmetric catalysis. Interactions involving aromatic rings are particularly pervasive. Therefore, ... -
Exploring and expanding the synthetic potential of a biocatalytic dynamic kinetic resolution
(The University of Edinburgh, 2021-07-31)The market demand for enantiopure non-canonical amino acids (NCAA) has been increasing in recent years, given the importance of these compounds as chiral building blocks employed in the synthesis of many pharmaceuticals ... -
Phenotyping the tumour microenvironment in non-small lung cancer using patient derived samples
(The University of Edinburgh, 2021-07-31)Lung cancers accounts for more deaths than other types cancer making it a significant cause of morbidity and mortality. Non-small cell lung cancer (NSCLC) is potentially curable via surgical resection, if diagnosed in ... -
Exploring the structure and function of key enzymes involved in microbial sphingolipid biosynthesis
(The University of Edinburgh, 2021-07-31)Sphingolipids (SLs) are a diverse class of lipid molecules derived from the amino acid L-serine and long chain fatty acids (e.g. carbon chain lengths C14-C26). When combined together these building blocks form a so-called ... -
Molecular dynamics based methods for the computation of standard binding free energies and binding selectivity of inhibitors of proteins of pharmaceutical interest
(The University of Edinburgh, 2021-07-31)The field of Computer Aided Drug Design (CADD) has experienced substantial developments over the last few decades thanks to a rapid growth incomputing power. In particular, Molecular Dynamics (MD) simulations and associated ...
