Royal (Dick) School of Veterinary Studies: Recent submissions
Now showing items 1-20 of 1030
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Getting Data Back to Farmers - slides from session with SEBI-Livestock Monitoring & Learning group
(2023-04-17)This session was presented to the SEBI-Livestock monitoring and learning group. The purpose was to share experiences and challenges with getting data back to farmers in the context of livestock development in low-and ... -
Investigation of quantitative magnetic resonance imaging and microRNA profiling of equine distal interphalangeal joint osteoarthritis
(The University of Edinburgh, 2023-05-23)Osteoarthritis (OA) is reported to be one of the most prevalent diseases in aging horses and it significantly affects high motion joints of the equine distal limb with the distal interphalangeal joint (DIPJ) frequently ... -
Development and validation of an in vitro porcine skeletal muscle model
(The University of Edinburgh, 2023-05-18)The projected rise in world population to 9.7 billion by 2050 will require an increased production of meat globally to meet human requirements for protein without compromising environmental and financial sustainability. ... -
Models and mechanisms of sexual dimorphism in cardiovascular calcification
(The University of Edinburgh, 2023-05-17)Cardiovascular calcification is the active process of calcification of the cardiovascular soft tissue. It is currently predicted to be present in over 70 % of the population aged 65 years and over. One of the most common ... -
Investigating the development of Peyer’s patches and the transcriptome of M cells in chickens
(The University of Edinburgh, 2023-05-15)Considering the approximately 8 billion world population in 2022 and its predicted growth rate of 1.1% per year, there is an increasing demand for food for this growing population. Poultry products such as meat and eggs ... -
Production and characterisation of dog CSFl-Fc protein
(The University of Edinburgh, 2016-12-20)Colony stimulating factor 1 (CSFI) is responsible for maintenance, proliferation and differentiation of cells of the mononuclear phagocyte system, which includes monocytes, macrophages and their progenitor cells. Macrophages ... -
Genetic analysis of the domestic cat in the United Kingdom; populations and diseases
(The University of Edinburgh, 2023-04-18)The domestic cat is one of the most popular pets in the world. It is estimated that 89–92% of domestic cats in the UK are non-pedigree Domestic shorthair (DSH), Domestic longhair (DLH), or Domestic semi-longhair cats (DSLH). ... -
Development of pluripotent stem cells from domestic and wild suidae for the study of host pathogen interactions in vitro
(The University of Edinburgh, 2023-04-17)African Swine Fever (ASF) disease is caused by infection of susceptible Suidae with African Swine Fever Virus (ASFV). In Eurasian domestic pigs, and closely related wild boar, ASF is characterised by a haemorrhagic fever ... -
Genetic and physiological factors affecting thermoregulation and resistance to body cooling in newborn lambs
(The University of Edinburgh, 1983)Lamb mortality is a serious source of economic loss to the sheep industry. Surveys have shown that up to 50% of the post-natal losses can be due either directly or indirectly to cold exposure. This thesis examines various ... -
Investigating the early interaction between Mycobacterium avium ssp paratuberculosis and the host using a bovine enteroid system
(The University of Edinburgh, 2023-03-27)Mycobacterium avium ssp paratuberculosis (MAP) is the causative agent of Johne’s disease (JD), a chronic granulomatous enteritis of ruminant’s prevalent world-wide. Infection of calves occurs through the faecal oral route, ... -
Visualising the bacterial pangenome: an analysis of the genetic content of staphylococcus aureus
(The University of Edinburgh, 2023-03-13)Bacterial genomes can be highly variable, with genetic material being frequently gained, lost, altered, and exchanged. Modern sequencing capabilities have enabled the sequencing of tens of thousands of genomes, and large-scale ... -
Precision breeding for piglet survival and the potential use of stress-related gastrointestinal microbiota biomarkers to improve porcine wellness
(The University of Edinburgh, 2023-02-15)In the UK, piglet survival rate from birth to weaning has reduced from 82.9 to 81.0% per litter from 2014 to 2021 due to a substantial increase in the average number of piglets per litter from 13 to 15. This reduction ... -
Investigation of host factors in influenza a virus infection
(The University of Edinburgh, 2023-02-14)Influenza A virus (IAV) causes a contagious respiratory disease which can be fatal in at risk populations. Seasonal epidemics of IAV infection are responsible for as many as 650,000 human deaths annually. Antiviral drugs ... -
Methods of inducing and assessing positive affective states in juvenile male Wistar rats
(The University of Edinburgh, 2023-02-09)The importance of animals having positive experiences is essential for animal welfare as the balance of positive and negative affective states can be seen as critical to determining an animal’s quality of life. However, ... -
Do UK grasslands have the ability to sequester more carbon? Assessment of stability and resilience to changing climate and management
(The University of Edinburgh, 2023-02-09)Soil organic matter (SOM) is the largest terrestrial pool of organic carbon (C). Carbon can persist in the soil due to several mechanisms, i) inherent chemical recalcitrance, ii) association with minerals in the soil and ... -
Role of endothelial cell dysfunction in cerebral small vessel disease using a novel rodent model
(The University of Edinburgh, 2023-02-07)Cerebral small vessel disease (SVD) is the most common cause of vascular dementia and can occur in combination with other neurodegenerative diseases, worsening clinical signs. SVD doubles a patient’s risk of developing ... -
Hardware accelerated imputation of dairy cattle genotypes using field programmable gate arrays (FPGA)
(The University of Edinburgh, 2020-08-04)[No Deposit Agreement] -
Metabolomic analysis of synovial fluid for early detection of palmar osteochondral disease in the equine metacarpophalangeal joint diagnosed with magnetic resonance imaging
(The University of Edinburgh, 2019-11-27)[No Deposit Agreement] -
Modulation of the faecal microbiota by the prebiotic lactulose in healthy dogs
(The University of Edinburgh, 2019-11-27)[No Deposit Agreement] -
Investigation of the molecular pathogenesis of the multi-host bacterial pathogen Staphylococcus aureus
(The University of Edinburgh, 2023-01-31)Staphylococcus aureus is a major human and animal bacterial pathogen that causes an array of diseases. The main aim of this thesis is to investigate the key host-pathogen interactions that underpin S. aureus infection. ...
