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ERA is a digital repository of original research produced at The University of Edinburgh. The archive contains documents written by, or affiliated with, academic authors, or units, based at Edinburgh that have sufficient quality to be collected and preserved by the Library, but which are not controlled by commercial publishers. Holdings include full-text digital doctoral theses, masters dissertations, project reports, briefing papers and out-of-print materials.

Information on current research activity including staff, projects and publications is available via the Edinburgh Research Explorer.

Now showing 1 - 40 of 41

Recent Submissions

Current Trends in Mediation: MEND Key Findings
(2026) PeaceRep consortium
The changing nature of peacemaking. We are seeing a shift in how mediation is undertaken. Efforts tend to be less connected, focus on issues that can be resolved more quickly, and often lack the ability to bring multiple strands of talks into a coherent whole.
How Peace Agreements Address Displaced Persons: Key Trends and Challenges
(PeaceRep: The Peace and Conflict Resolution Evidence Platform, 2026) Wilson, Robert; Henry, Niamh; Epple, Tim
There is a concerning mismatch between the rise in displacement and the decline in peace agreements addressing it. At the end of 2024, an estimated 123 million people were forcibly displaced, with 73.5 million Internally Displaced Persons (IDPs) displaced by conflict and violence. Yet, only 16% of international- and national-level agreements signed between 1990 and 2024 address displacement in a substantive way. While global displacement has been increasing over time, reaching record levels since 2019, the proportion of new peace agreements addressing displacement substantively has been declining.
Changing Peacemaking Practice: PA-X Key Findings
(2026) PeaceRep consortium; Peace agreements
more fragmented, and increasingly internationalised. Since 1990, there have been over 2,200 formal, written, publicly available peace agreements across more than 180 peace processes. Most relate to conflicts within states, but the landscape of peacemaking has changed: 1. formal, structured peace processes are no longer the norm; 2. agreements are shorter and less ambitious - fewer human rights and democratic transition provisions; and, 3. contemporary peacemaking increasingly operates through fragmented and “multimediation” environments involving multiple actors, tracks, and negotiation spaces.
Queer(ing) Antimicrobial Stewardship
(The University of Edinburgh, 2026) Ledin, Chase; Locke, Daniel; Economic and Social Research Council (ESRC)
Queer(ing) Antimicrobial Stewardship is a 5-page comic book that explores Dr Chase Ledin's ongoing research about antibiotic stewardship within sexual healthcare in the United Kingdom. The comic book tells the story of an individual who decides to use DoxyPEP as STI prevention and the individual, community, and societal implications of using this antibiotic. The comic book highlights key discourses within antibiotic resistance and stewardship narratives, and derives from interviews and focus groups with clinicians, health specialists, patients, and community members across England and Scotland.
Augmenting clinical risk prediction of cardiovascular disease through multi-omics
(2026-05-13) Chybowska, Aleksandra Daria; Marioni, Riccardo; Evans, Kathy; Price, Jackie; Medical Research Council (MRC); Medical Research Council Doctoral Training Program; University of Edinburgh: College of Medicine and Veterinary Medicine
BACKGROUND: The serum proteome can provide valuable insights into the development and progression of diseases. This is particularly important for cardiovascular disease (CVD), a leading cause of death worldwide. In this large-scale cohort study, we employ an untargeted massspectrometry- based approach to explore associations between highly expressed proteins, incident CVD (analysed as six individual outcomes and one composite outcome) and all-cause mortality. METHODS: The abundances of 439 proteins and protein groups quantified by mass spectrometry in serum were related to incident outcomes in 8,343 Generation Scotland participants (age 40–69 years), who were free of CVD at baseline (nall_cause_death=618, ncomposite_CVD=666, follow-up ≤17 years). Cox proportional hazards (PH) models were run before and after adjustment for preselected known CVD risk factors. Sex-specific effects were explored. A protein-based risk score for composite CVD outcome was developed using penalised regression. RESULTS: Forty-eight high abundance serum proteins and protein groups were significantly associated with incident CVD and death outcomes (PBonferroni<1.14x10-4), including 24 associations not reported in the Open Targets database. Proteins involved in immune and oxidative stress responses were associated with composite CVD (Immunoglobulin heavy variable 3/OR16-9, Hazard Ratio per SD (HR)=0.85 [95%CI 0.79,0.92]) and death (Alpha-1-antitrypsin, HR=1.27 [1.17, 1.38]), while heart failure was linked to proteins playing a role in lipid metabolism (Apolipoprotein A-II, HR=0.70 [0.59, 0.84]) and complement cascade (Complement C1q subcomponent subunit B, HR=1.40 [1.18, 1.66]). Applied to the test set, the proteomic risk score improved 17-year incident CVD prediction over models including age, sex, and nine lifestyle and clinical risk factors (ΔAUC = 0.010, ROC P = 0.013). CONCLUSION: The highly abundant serum proteome, readily assessed by mass spectrometry, reveals candidate biomarkers for incident CVD and provides predictive value for early risk stratification.