Edinburgh Medical School
Edinburgh Medical School is one of two schools at the College of Medicine and Veterinary Medicine at the University of Edinburgh. The Edinburgh Medical School integrates research and teaching across our three Deaneries: Biomedical Sciences, Clinical Sciences and Molecular,Genetic and Population Health Sciences.
Collections in this Community
Recent Submissions
-
Monitoring disease activity in large vessel vasculitis
(The University of Edinburgh, 2023-02-07)Large vessel vasculitis (LVV), including giant cell arteritis (GCA) and Takayasu arteritis (TAK), is the most common form of primary vasculitis and is characterised by chronic inflammation of medium and large arteries. ... -
Molecular evaluation of early bladder cancer to improve clinical decision making
(The University of Edinburgh, 2023-02-06)Bladder cancer (BC) is the 12th most common cancer worldwide, with approximately 5,300 deaths every year in the UK. Currently, diagnosis is only possible through the assessment of the tissue by invasive techniques such as ... -
Monitoring the spread of antibiotic resistance in wastewater
(The University of Edinburgh, 2023-02-06)BACKGROUND: Antibiotic resistant bacterial infections are causing a growing amount of morbidity and mortality. Effective control and prevention relies on good data on the current burden of antibiotic resistance (ABR). ... -
Representation of perceptual uncertainty in mouse primary visual cortex
(The University of Edinburgh, 2023-02-06)Uncertainty in various modalities (perceptual, motor, cognitive) is a fundamental problem that the brain must solve to ensure optimal responses to the demands of the environment. It has been shown theoretically that the ... -
Establish the extended regulon of the RamA regulator by performing ChIPseq
(The University of Edinburgh, 2020-08-07)[No Deposit Agreement] -
Pro-regenerative role of tgfβ-1a after spinal cord injury in zebrafish larvae
(The University of Edinburgh, 2019-11-25)[No Deposit Agreement] -
Investigating outer membrane vesicular structure and function in Klebsiella pneumoniae
(The University of Edinburgh, 2019-10-25)[No Deposit Agreement] -
Clinical role of lung clearance index in the assessment of cystic fibrosis lung disease
(The University of Edinburgh, 2019-05-31)[No Deposit Agreement] -
Intestinal helminth infection and inflammatory responses in the murine brain
(The University of Edinburgh, 2019-06-29)Heligmosomoides polygyrus is a solely enteric helminth parasite that infects mice. It has recently been reported that infection of this parasite elicits a systemic increase in type-I interferon expression. This response ... -
Microglia regulate myelin growth and integrity in the central nervous system white matter
(The University of Edinburgh, 2023-01-30)Disruption of myelin structure occurs with ageing and neurodegenerative disease, and involves myelin which is outfolding, unravelling, less compact, and thicker. This is associated with nerve dysfunction and cognitive ... -
Pre-clinical screening for re-purposed and novel compounds that reduce synucleinopathy, and investigation of LRRK2 activity and VPS35 function within human cell culture models of Parkinson’s disease
(The University of Edinburgh, 2023-01-30)Human pluripotent stem cell (PSC) models of Parkinson’s disease (PD) are a promising tool for drug screening and for investigating disease mechanism. Mutations within LRRK2 are the most common cause of familial PD, where ... -
Role of FOXP1 in adipose progenitor maintenance during ageing
(The University of Edinburgh, 2023-01-27)Ageing is described as an inevitable functional decline over time, and is known to affect almost all living organisms. Adipose tissue (AT) has been viewed as a highly dynamic and adaptable organ and has been uncovered as ... -
Investigating the metabolic plasticity of inflammatory neutrophils during infection
(The University of Edinburgh, 2023-01-27)Neutrophils are required to function and survive under challenging conditions characterised by tissue hypoxia and nutrient scarcity. Neutrophils are well suited to rapidly respond to infection and engage with metabolic ... -
Investigating the genetic and immunological aetiology of myalgic encephalomyelitis/chronic fatigue syndrome
(The University of Edinburgh, 2023-01-25)This thesis describes two investigations into the disease Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), specifically its genetic aetiology and immune system alterations. The first study investigated the ... -
Health-related decision-making in its personal, social and health service contexts: a critical review of relevant findings from seven publications and consideration of their contribution to understandings of decision-making and the wider field of applied health services research
(The University of Edinburgh, 2023-01-25)Health-related decision-making, in particular patients’ involvement in decision-making about their treatment and care, has been an important and enduring concern for many practitioners and researchers working in applied ... -
In-depth enquiry into the implementation of a large-scale social health protection scheme in the context of the drive towards universal health coverage in Khyber Pakhtunkhwa, Pakistan
(The University of Edinburgh, 2023-01-24)BACKGROUND: In the wake of Goal 3 (ensuring healthy lives and promoting well-being for all at all ages) of the Sustainable Development Goals (SDGs) and the resulting push for Universal Health Coverage (UHC), Pakistan’s ... -
Role of ion channels in controlling murine corticotrophin excitability
(The University of Edinburgh, 2023-01-24)Anterior pituitary corticotrophs are integral components of the hypothalamus-pituitary-adrenal (HPA) axis controlling the neuroendocrine stress response. A variety of ion channels regulate intrinsic electrical excitability ... -
Do respiratory epithelial cells ‘remember’ early life microbial exposure through epigenetic changes?
(The University of Edinburgh, 2023-01-23)The adaptive immune system was considered to be the sole arm of immunity that can form a memory of past infections. In recent years this paradigm has been contested, following discoveries that many innate immune cells ... -
Resource use and costs at the end of life: essays on common ways to collect data on resource use and derive costs at the end of life in a UK setting
(The University of Edinburgh, 2023-01-19)BACKGROUND: Within the given environment of scarce health care resources and increasing demands on the health care system, it is imperative to organise health care in the most efficient manner. Sustainability of the overall ... -
Defining the role of neutrophils in paracetamol-induced liver injury and regeneration
(The University of Edinburgh, 2023-01-19)Neutrophils, the most abundant white blood cell in mammals, are crucial innate immune cells required as the first line of defence against invading pathogens or foreign material. They are also recruited in response to ...
