Chemistry thesis and dissertation collection
The School of Chemistry at the University of Edinburgh is the top rated for teaching and research in Scotland.
Presented here is a selection of research from the School
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Recent Submissions
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Dinuclear cerium tetraphenolate complexes: from Lewis acid catalysts to redox chemistry
(The University of Edinburgh, 2022-04-28)Molecular cerium complexes provide opportunities to take advantage of intrinsic characteristics of cerium, such as its strong Lewis acidity and redox chemistry for homogenous catalysis, and its high earth abundance has ... -
Interactions of halogens
(The University of Edinburgh, 2022-04-26)As an analogue of the ubiquitous hydrogen bond, interest in halogen bonding has garnered interest since the turn of the twenty-first century. The orthogonal nature and occasionally surprising characteristics of halogen ... -
Synthesis and magnetic properties of Fe-based homo- and heterometallic clusters
(The University of Edinburgh, 2022-04-21)Historically, polynuclear FeIII-O clusters have been at the heart of the study of molecular magnetism. From the study of [FeIII2-(μ-O)] dimers detailed magneto structural correlations were developed that can be applied to ... -
α-Oxoamine synthases for industrial biocatalysis
(The University of Edinburgh, 2022-04-18)α-Oxoamine synthase (AOS) enzymes are key pyridoxal-5’-phosphate (PLP)-dependent, C-C bond-forming enzymes, which catalyse a Claisen-like condensation reaction between an L-α-amino-acid (L-AA) and an acyl-CoA thioester, ... -
Molecular modelling of lubricant-solid interactions that control friction and wear
(The University of Edinburgh, 2022-11-04)Lubricants are used widely in industry to reduce the effects of friction and wear. Lubricant formulations for engine applications are typically composed of a base oil and various additives, each having a different function. ... -
Synthesis of new high-pressure A-site manganite perovskites and investigation of their magnetic properties
(The University of Edinburgh, 2022-07-04)Perovskites, with the general formula, ABO3, have been extensively studied due to their large variety of intriguing electronic and magnetic properties, which can be achieved via a number of possible chemical compositions. ... -
Adsorbents for the removal of organic and inorganic contaminants from water
(The University of Edinburgh, 2022-03-24)The molluscicide metaldehyde has been frequently detected in ground and surface waters in concentrations exceeding the 0.1 μg L-1 EU regulatory limit, as industrial Granular Activated Carbon (GAC) has been proven inadequate ... -
Development of hydrogen deuterium exchange mass spectrometry methodologies for the analysis of bacterial nano-compartments
(The University of Edinburgh, 2022-03-23)Hydrogen deuterium exchange mass spectrometry (HDX-MS) is a versatile biophysical technique used in a variety of applications within structural proteomics. The key advantages of HDX-MS are that it can provide insight ... -
Synthesis and characterisation of novel phthalocyanine-based porous materials
(The University of Edinburgh, 2022-03-21)Phthalocyanines are planar aromatic macrocycles whose unique properties give them a wide variety of potential applications, particularly as pigments and dyes, but also in solar cells, photodynamic therapy and as catalysts. ... -
Exploiting bifunctional fusion enzymes from biosynthetic pathways as biocatalysts
(The University of Edinburgh, 2022-03-21)Biocatalysis is anenvironmentally friendly alternative to traditional synthetic techniques andleads to the production of products with high enantio-, stereo- and chemo-selectivity. Conducted at ambient temperature and ... -
Force fields for biomolecular simulations: from supra-molecular bio-inspired catalysts to protein- inhibitors complexes
(The University of Edinburgh, 2022-03-18)Over the past decades, molecular modelling and molecular dynamics (MD) simulations have become well- established disciplines, providing special tools for the study of chemical and biological processes. To perform classical ... -
Multimetallic main group prophenol catalysts for homo- and multi-block polyester synthesis and depolymerisation
(The University of Edinburgh, 2022-03-14)Cyclic ester ring-opening polymerisation (ROP) is an efficient route to prepare biodegradable polyesters, such as poly(lactide) (PLA), poly(ε-caprolactone) (PCL), poly(3-hydroxybutyrate) (PHB) and poly(δ-valerolactone) ... -
Investigations of novel dimerisations and brevianamide-type alkaloids
(The University of Edinburgh, 2022-03-11)This thesis describes work towards two discrete projects; Chapter 1-3 methodology development of enantioconvergent reactions, Chapter 5-7 total synthesis of brevianamide type natural products. Both of these studies are ... -
Transborylation: borane-catalysed hydroboration and hidden catalysis
(The University of Edinburgh, 2022-03-11)Hydroboration is a textbook reaction, finding application in total synthesis and the fine chemicals industry. The versatility of the organoborane products to be transformed into an array of different functionalities makes ... -
Natural product inspired amine donor for transaminase biocatalysts
(The University of Edinburgh, 2022-03-09)The synthesis of chiral amines by transaminase (TA) biocatalysts is a valued and attractive strategy used by the pharmaceutical, agrochemical and chemical industries, due to the exquisite selectivity and environmentall ... -
Investigation of Europium B-Diketonate complexes as spectral converters for solar cells
(The University of Edinburgh, 2022-02-23)Photovoltaic technologies for solar energy conversion are promising routes to renewable energy generation. A major difficulty in improving photovoltaic energy conversion efficiency lies in the spectral mismatch between ... -
Smarter staining: new biocatalytic systems for multiplexing histological staining
(The University of Edinburgh, 2021-11-17)Immunohistochemistry (IHC) is an important technique with applications in disease diagnosis, biological research and drug development. Recent developments in personalised medicine, mean that there is a rising demand ... -
Representativeness and application of long-term trace gas and photolysis measurements for evaluating local air quality
(The University of Edinburgh, 2021-11-12)Networks of long-term measurements of trace gases are critical for understanding spatio-temporal trends in air pollutants. This data is used to assess long-range and trans-boundary transport of emissions, quantify effects ... -
Advanced characterisation study of ultrasound contrast bubbles in their natural hydrated state
(The University of Edinburgh, 2021-11-27)This study presents a systematic investigation on in-house ultrasonic contrast agents, known as microbubbles (MBs), in their natural hydrated state. Contrast microbubbles have strong acoustic scatter profiles that ... -
Alkyne Metathesis: a new tool for the self-assembly of complex molecular architectures
(The University of Edinburgh, 2021-11-27)Macrocyclic scaffolds have attracted considerable attention over the past two decades because of their unique properties and promising potential in a wide range of applications in drug discovery, material science and ...
