The examination of the gastric contents as an aid to the diagnosis of carcinoma of the stomach
dc.contributor.advisor
en
dc.contributor.author
Dunlop, Derek Melville
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dc.date.accessioned
2018-09-13T15:50:20Z
dc.date.available
2018-09-13T15:50:20Z
dc.date.issued
1927
dc.description.abstract
As the result of my investigations the
following conclusions have been arrived at. It must
he realised, however, that, as it has only been
possible to study a limited number of oases, certain
of these conclusions must not be taken as dogmatic
assertions, but rather as expressions of opinion based
upon a limited number of results.
en
dc.description.abstract
1. Gastric carcinoma may be diagnosed or excluded in the vast majority of cases, by
examination of the stomach contents alone.
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dc.description.abstract
E. The results of the gastric analysis on
which importance should be placed, in the
diagnosis of this disease, are the presence
of: (a) Achlorhydria.
(b) Lactic acid.
(c) Blood.
(d) Evidences of stagnation.
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dc.description.abstract
3. Absence of free acid and the presence of
lactic acid are found in the great majority
of patients suffering from gastric carcinoma, and such a dual finding, with the exception of carcinoma of the oesophagus,
probably occurs in no other condition.
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dc.description.abstract
4. The absence of lactic acid in stomach
contents which show no free acid, or the
discovery of large quantities of free
hydrochloric acid make the presence of gastric carcinoma exceedingly improbable.
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dc.description.abstract
5. The absence of free acid and the presence
of lactic acid is not necessarily evidence
of an advanced condition of the carcinoma,
nor is the presence of free acid necessarily evidence of an early stage in the growth.
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dc.description.abstract
6. Lactic acid found in the stomach is not
invariably caused by the fermentation of
stagnating gastric contents, but may be
sareolaetic acid produced by the tissues involved by the growth. It may therefore
occur in the stomach contents when no pyloric stenosis is present.
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dc.description.abstract
7. Graphs of the total acidity curve in
gastric carcinoma can usually be distinguished from those found in pernicious anaemia
and primary achylia gastrica from the shape
of the curve.
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dc.description.abstract
8. The congo red and dimethyl tests for
free hydrochloric acid in the gastric contents are not trustworthy, since: (a) They do not indicate free hydrochloric acid when it is present
in very small quantities.
(b) They react to large quantities of lactic acid in the same way
as they react to free hydrochloric acid.
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dc.description.abstract
9. GUNZBERG'S test, when the reagent is
freshly prepared, is an entirely reliable
one for the presence of free hydrochloric
acid.
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dc.description.abstract
10.
UFFELMANN'S test for lactic acid is
valueless, as it gives a positive reaction
with many other substances, which may be
found in the stomach contents, besides
lactic acid.
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dc.description.abstract
11. MACLEAN'S test for lactic acid is simple
and trustworthy.
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dc.identifier.uri
http://hdl.handle.net/1842/32014
dc.publisher
The University of Edinburgh
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dc.relation.ispartof
Annexe Thesis Digitisation Project 2018 Block 20
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dc.relation.isreferencedby
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dc.title
The examination of the gastric contents as an aid to the diagnosis of carcinoma of the stomach
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dc.type
Thesis or Dissertation
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dc.type.qualificationlevel
Doctoral
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dc.type.qualificationname
MD Doctor of Medicine
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