Harvey, Thomas Blair

2018-09-13T15:59:44Z

2018-09-13T15:59:44Z

1935

While I was resident physician in the wards of the Royal Infirmary, Edinburgh, Dr. Chalmers Watson suggested I should study the injection of iodine intravenously. I chose twelve cases at random, and the following is an account of the preparation used; the technique; and the results.

The preparation used consisted of:- Iodine i drachm; Potassium Iodide 1 drachm; Distilled Water 5 ounces; Minims 20 of the above in 10 cc. Normal Saline was the quantity used for each injection, i.e. gr. 0.5 of Iodine.

THE TECHNIQUE: The injection was given intravenously at 11 A.M. For some days prior to the injection all patients were placed on a uniform diet, etc. with a view to eliminating as far as possible any error arising from altered environment.

Each experiment lasted three days.

Observations were made on temperature, respiration rate, pulse rate, systolic and diastolic pressure; urine per hour (quantity, specific gravity, urea concentration, and abnormal constituents); influence on the leucocyte count; anti the Basal Metabolic Rate ( B.M.R.)

Careful observations were taken at frequent intervals throughout each day, noting the patients general condition, size of thyroid, and any variations in the symptomatology, both subjective and objective.

On the first day control observations were made. On the second day Iodine was administered intravenously at 11 A.M., and the results carefully studied; while on the third day observations were made on similar lines. For the following few days the patients" condition was carefully watched.

http://hdl.handle.net/1842/32396

The University of Edinburgh

Annexe Thesis Digitisation Project 2018 Block 20

Observations on the action of Iodine

Thesis or Dissertation

Doctoral

PhD Doctor of Philosophy