McMurtrie, Alexander C. B.

2019-02-15T14:36:38Z

2019-02-15T14:36:38Z

1910

This thesis has been undertaken with the object of investigating the various types of temperature met with in cases of Lymphadenoma, or Hodgkin's Disease.

At the outset the question may well be asked, "What is Hodgkin's disease?" In the past so much confusion has arisen over the terms Lymphadenoma, Lymphosarcoma, Malignant Lymphoma, Pseudo- Leukaemia, etc. that I feel it is necessary before entering upon a discussion of a disease of such obscure origin to define what is meant by the term "Lymphadenoma".

The best definition that I have been able to find is that given by Gowers in Reynold's System of Medicine in 1879.

"An affection characterised by a widely spread enlargement of the lymphatic glands, commonly also by an enlargement of the spleen and by progressive armada.. The enlargement of the glands and spleen is due to the growth in them of adenoid tissue having a tendency to undergo a fibroid transformation, and in the spleen to be localised in isolated masses. In many cases disseminated growths of similar structure occur in other organs, especially the intestinal canal, the liver, and the kidneys. The blood presents invariably a diminution in the number of red blood corpuscles, occasionally an increase in the white corpuscles, usually inconsiderable".

Before passim; or to the subject of this thesis I should like to state in reference to the much discussed relationships of Tuberculosis to Lymphadenoma that my views are entirely in accordance with the conclusions arrived at by Butlin (trans.Path.Soc.Lond., Vol.LIII, 1902, p.297), namely, that Lymphadenoma is certainly not tubercle, but that it does not exclude tubercle or render a patient in the least degree immune to an attack of tubercle.

For convenience the thesis presented has been divided into four sections.

SECTION I. Case of Lymphadenoma illustrating a relapsing type of temperature with periodic variations in the size of the spleen and lymphatic glands corresponding to the variations in the temperature.

SECTION II. A review of the literature on the subject of relapsing temperatures in lymphadenoma.

SECTION III. Other cases of Lymphadenoma showing various types of temperature.

SECTION IV. Conclusions.

All the cases of Lymphadenoma, investigated have been under observation at Paddirngton Green Children's Hospital, London.

http://hdl.handle.net/1842/35286

The University of Edinburgh

Annexe Thesis Digitisation Project 2019 Block 22

Lymphadenoma: with special reference to the temperature

Thesis or Dissertation

Doctoral

MD Doctor of Medicine