Comparative study of some changes in the blood and cerebral capillaries in mice during infection with Babesia rodhaini and Babesia microti
dc.contributor.advisor
Wilde, J. K. H.
dc.contributor.advisor
MacLeod, W.
dc.contributor.author
Gamble, Peter Guy
dc.contributor.sponsor
Overseas Development Authority
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dc.date.accessioned
2023-09-28T14:55:44Z
dc.date.available
2023-09-28T14:55:44Z
dc.date.issued
1974
dc.description.abstract
Methods of sampling mice for "blood examination and "brain crush preparation, are described.
Erythrocyte, leucocyte and brain capillary parameters were studied in the normal mouse, and these were measured throughout infections with Babesia rodhaini and B. microti in order to compare any differences in response to these parasites.
A number of differences between the infections were established. Babesia rodhaini produced a disease of high
mortality with a normocytic normochromic anaemia. The white cell response was restricted to the neutrophil series. Babesia microti produced a non-fatal disease with a macrocytic, normochromic anaemia. The white cell response was massive, involving the neutrophils, lymphocytes and monocytes.
In neither disease was any evidence, to suggest that cerebral babesiosis played an important part in the pathology of the disease, found.
en
dc.identifier.uri
https://hdl.handle.net/1842/40974
dc.identifier.uri
http://dx.doi.org/10.7488/era/3725
dc.language.iso
en
en
dc.publisher
The University of Edinburgh
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dc.subject
blood
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dc.subject
cerebral capillaries
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dc.subject
mice
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dc.subject
mice during infection
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dc.subject
Babesia rodhaini
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dc.subject
Babesia microti
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dc.subject
brain crush preparation
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dc.subject
Erythrocyte
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dc.subject
leucocyte
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dc.subject
brain capillary parameters
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dc.subject
normochromic anaemia
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dc.title
Comparative study of some changes in the blood and cerebral capillaries in mice during infection with Babesia rodhaini and Babesia microti
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dc.title.alternative
A comparative study of some changes in the blood and cerebral capillaries in mice during infection with Babesia rodhaini and Babesia microti
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dc.type
Thesis or Dissertation
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dc.type.qualificationlevel
Masters
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dc.type.qualificationname
MSc Master of Science
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