A study of factors concerned in variations of the tuberculin skin reaction occuring in health and disease during adult and child life

Abstract

1. Variations in the intensity of the tuberculin skin reaction are related to:-(a.) the normal development and decline of bodily function,(b.) depression of bodily function associated with: - (1.) Prolonged confinement to bed. (2.) Anaemia. (3.) Malnutrition. (4.) Cardiac insufficiency. (5.) Syphilis. (6.) Influenza. (7.) Measles. (8.) Physiological events in the female life.2. Tuberculin skin reactions attain their maximum reliability in children owing to the relative infrequency in the early years of life of the conditions found to modify skin reactivity to tuberculin.3. A severe tuberculin skin reaction occurring in a child is an indication of impending failure of local or general resistance to tuberculous infection.