Investigation into the use of mice to monitor the protective effect of Fasciola immune serum

Abstract

A review of the literature of immunity to fascioliasis is presented. Following a description of the materials and methods used, an account of attempts to demonstrate immunity to Fasciola hepatica in mice by passive transfer of immune serum from rats is given. No immunity to F. hepatica was demonstrated.

The possible reasons for this are discussed and suggestions are made for further studies.