Ramsay, Mabel L.

2019-02-15T14:17:45Z

2019-02-15T14:17:45Z

1912

My aim in writing this Thesis is to draw attention to the fact that the Bacillus Coli Communis is found in the urine more frequently than has hitherto been supposed, and its presence there is indicative of a pathological state of the body. As more is known and studied it will no doubt be possible to describe an infection of the Bacillus Coli Communis as a definite clinical entity, and many diseases described to -day under se- carate headings may one day be described as a stage or phase of a Bacilli Coli Septicaemia or Toxemia, Acute or Chronic. The Bacillus Coli Communis is found in the urine either in pure culture or in association with one or more organisms, but is predominant. In the latter mixed infections it is difficult to judge whether the pathogeneity of the Bacillus Coli Communis is increased or diminished when so associated. One feels that evidence points to an increase of virulence when so associated. In many cases of:- (1) Nephritis, or Bright' s Disease in various forms, the Bacillus Coli Communis is so frequently found that one thinks that at a subsequent date we may regard Nephritis as describing one of the stages of a chronic Bacillus Coli Communis infection. (2) Pyelo-nephritis one regards as being almost invariably associated with Bacillus Coli Communis, with also presence of Calculi. (3) Even in Tuberculosis of the Genito -Urinary Tract this organism is so frequently found associated that one ventures to wonder which had the priority. Did the Bacillus Coli Communis by its presence and toxins produce the necessary stage to permit of the second invasion by the Tubercle Bacillus? (4) Attention will also be drawn to cases ap arently not associated with any clinical symptoms of Genito-Urinary diseases other than.the presence of the Bacillus Coli Communis in the urine as evidenced by (a) Generalised infections, (b) Toxemia as seen in the Eye Cases quoted. One proposition will be maintained, i.e. that the presence of the Bacillus Coli Communis is indicative of a pathological state, and that in normal healthy individuals there should not be any micro-organisms present in the urine. The majority of the cases quoted are of a specific genitourinary infection.

http://hdl.handle.net/1842/33625

The University of Edinburgh

Annexe Thesis Digitisation Project 2019 Block 22

The invasion of the human body by the bacillus coli communis: pathological effects, etiology, clinical symptoms and treatment

Thesis or Dissertation

Doctoral

MD Doctor of Medicine