Anaphylaxis and sensitisation: with special reference to the skin and its diseases

Abstract

The object of this Thesis is to describe and dîscuss the phenomena of anaphylaxis and sensitisation in so far as they affect the skin. Before taking up each section separately, it will be well to give a short general description of our present knowledge of these phenomena and an explanation of the numerous terms which will he used throughout this work.Anaphylaxis was the term introduced by RICHET to describe the series of phenomena which occur on reinjection into animals, after an interval of several days, of certain substances which were harmless on first injection. As the animal had been rendered more susceptible to the substance injected, RICHET thought the condition was the opposite of Prophylaxis or Immunity, and gave it the name Anaphylaxis,,