Audio-analgesia and Multi-disciplinary Pain Management: A Psychological Investigation into Acute, Post-operative Pain
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Abstract
Background: Audio-analgesia, the ability of music to reduce the perception of
pain, has been a significant field of research in the past decade. This study aimed to investigate
the impact of the musical constructs of harmonicity and rhythmicity on acute,
post-operative pain.
Method: 98 patients scheduled for primary total knee arthroplasty were randomly allocated
at their pre-admissions clinic to one of four music listening groups, receiving
commercially-available music. The participants in the experimental groupings were
randomised according to the musical constructs of high/low harmonicity and rhythmicity
(four possible groups; + +, + –, – +, – –). Music groups were compared against
a silent control group, receiving quiet relaxation (with headphones). After surgery
using a standardised anaesthetic regiment, all participants undertook a 15-minute listening/
silent intervention on the ward for each day of their in-patient stay (max. 5
days). The primary endpoint was pain intensity. Salivary cortisol concentrations and
mood stability were also monitored. Qualitative data was collected via daily feedback
and assessed through thematic category analysis.
Results: A significant reduction in pain intensity from pre- to post-test was shown for
all participants (p < 0:0005), but with no difference between groups (F(4;68) = 1:331,
NS). Quiet relaxation (mean change: 22.27%) was as effective as music listening
(mean change: 37.47%). Salivary cortisol concentrations showed an interaction between
music with high harmonicity and high rhythmicity (+ +) and music of low harmonicity
and rhythmicity (– –). + + music reduced cortisol concentration to a greater
extent on Day 1 (p < :05) than – – music. There was no significant difference between
groups in mood disturbance. Qualitative data revealed four thematic categories of
response: psychological, physiological, musicological and methodological, overall indicating
that patients utilised their intervention as a distracting and relaxing cognitivecoping
strategy.
Conclusion: Music is a viable therapeutic medium which reduced pain, as effectively
as quiet relaxation. Compositional constructs were minimally active in the degree of
analgesia and physiological changes experienced by patients, but where this did occur,
it could be related to Berlyne’s inverted-U model of musical preference (Berlyne,
1971). The positive reception of the interventions and the associated benefits, supports
the inclusion of cognitive-coping strategies in multi-modal care pathways.
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