The modern treatment of pulmonary tuberculosis

Abstract

From the evidence available the following conclusions are reached:- The oedema of cardiac failure results from increased venous pressure, a general increase of body fluids and perhaps some increased capillary permeability from anoxia. The oedema of thrombophlebitis is due principally to a local rise in venous pressure but also to the vasodilator action of metabolites. In advanced cancer of the liver protein intake and synthesis are diminished, and fluid retention may occur if the anti -diuretic hormone is not destroyed. The hypoproteinaemia and consequent oedema of the Kimrnelstiel-Wilson syndrome results from urinary loss of albumin. Finally, the oedema of acute nephritis cannot yet be explained. satisfactorily.From the evidence available the following conclusions are reached:- The oedema of cardiac failure results from increased venous pressure, a general increase of body fluids and perhaps some increased capillary permeability from anoxia. The oedema of thrombophlebitis is due principally to a local rise in venous pressure but also to the vasodilator action of metabolites. In advanced cancer of the liver protein intake and synthesis are diminished, and fluid retention may occur if the anti-diuretic hormone is not destroyed. The hypoproteinaemia and consequent oedema of the Kimrnelstiel-Wilson syndrome results from urinary loss of albumin. Finally, the oedema of acute nephritis cannot yet be explained. satisfactorily.The five cases described have demonstrated some of the conditions in which oedema may occur , the inclusion of others such as subacute nephritis, famine oedema, filiariasis and toxaemia of pregnancy would have made a more complete picture. It is however evident that the mechanism of oedema production is a complex matter.