Late renal and cardio vascular effects of scarletinal nephritis

Abstract

This investigation is our attempt to find an answer to two main questions.(1) Is the acute scarletinal nephritis in childhood or youth ever the beginning of a chronic nephrit :is, which may manifest itself in later years? And if it does, is it a frequent termination?(2) Does an acute scarletinal nephritis which appears to have healed, leave any traces of organic change, or functional impairment of the kidneys or other organs, in particular the cardio vascular system?Subsidiary questions arose in the course of the enquiry and are discussed.The problem having thus been defined, the most practical method of approach at once presented itself for consideration - as regards the kidneys, how to exclude or confirm the presence of a gross lesion known to have been present during the scarletinal nephritis, and how best to detect the earlier stage of functional impairment.